Ultrastructure of high altitude pulmonary oedema.

Unravelling the Pathogenesis of Severe COVID-19 Pneumonia: Are There Possible Insights From High Altitude?

High altitude-induced pulmonary oedema.

Almost one mountain trekker or climber out of two develops several symptoms of high altitude illness after a rapid ascent (> 300 m/day) to an altitude above 4000 m. Individual susceptibility is the most important determinant for the occurrence of high altitude pulmonary oedema (HAPE). Symptoms associated with HAPE are incapacitating fatigue, chest tightness, dyspnoea at the slightest effort, or...

High altitude pulmonary oedema (HAPE) in an Indian pilgrim.

Increasing number of Hindu pilgrims visit the Himalayas where some of them suffer from high altitude illness including the life threatening forms, high altitude pulmonary oedema (HAPE) and high altitude cerebral oedema. Compared to tourists and trekkers, pilgrims are usually ignorant about altitude illness. This is a case of a pilgrim who suffered from HAPE on his trip to Kailash-Mansarovar and...

Ultrastructure of the lung in chronic hypoxia.

The most striking changes in the lungs in response to prolonged alveolar hypoxia occur in the small pulmonary arteries and arterioles. The influence ofchronic hypoxia on these small vessels has been subjected to extensive physiological investigation and to pathological examination by light and electron microscopy. The lung parenchyma, too, may be modified, but usually in response to brief sever...

No evidence for interstitial lung oedema by extensive pulmonary function testing at 4,559 m.

The aim of the present study was to better understand previously reported changes in lung function at high altitude. Comprehensive pulmonary function testing utilising body plethysmography and assessment of changes in closing volume were carried out at sea level and repeatedly over 2 days at high altitude (4,559 m) in 34 mountaineers. In subjects without high-altitude pulmonary oedema (HAPE), t...